Welcome to Brno!

Brno is the heart of South Moravia and the capital of the region. You will fall in love with the city thanks to its cosmopolitan atmosphere and friendly citizens. The city offers a wide selection of entertainment and experiences to suit the taste of every visitor. Don’t forget to try the amazing traditional cuisine, beer and wine. Come discover the charm of Brno.
Thanks to its rich history and medieval and modern architecture, Brno truly deserves to take a place among beautiful capitals and great cities of Eastern Europe, such as Bratislava, Prague, Budapest or Vienna.

General Information

Local organizers

Jaroslav Sterba
Zdenek Pavelka
Ondrej Slaby
Daniela Kodytkova


Meeting will be held in the Hotel Holiday Inn, located in Brno https://www.hibrno.cz/en/


Registration fee is €50 and covers meeting admission, all meals and optional trip to J.G. Mendel´s museum.


The meeting starts Monday morning, January 28th with registration, pre-meetings, and opening reception. The meeting ends Tuesday afternoon, January 29th,2019.




€ 50.– Until January 18th 2019

What is included

The registration fee includes all meeting meals, coffee breaks and optional trip to the J.G. Mendel´s museum.


Registration fee should be wired via bank transfer until 18th January.

For onsite registration, only payments in cash will be accepted.

For foreigners:

IBAN:    CZ78 0100 0000 0035 0377 0297


for CZ:

ACCOUNT NUMBER: 3503770297/0100 (Komerční banka)


Upon a receipt of the registration fee, each participant will receive a confirmation of registration. Please bring the receipt to the registration desk at the congress centre as a proof of your registration.

Cancellation / Refund Policy

Refunds of registration fees, after deduction of 50% of administrative fee, may be submitted in writing to the Administrative Secretariat at PO Dpt Brno until 18th January 2019. No refunds will be possible after this date.


January 27, 2019

18:00 – 20:00 REGISTRATION

January 28, 2019

09:00 – 09:05 Welcome
Jaroslav Štěrba
09:05 – 09:35 Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?
Fatma El-Khouly
09:35 – 09:55 Survey regarding the impact of the revised 4th edition of the WHO Classification of Tumours of the Central nervous System (2016) on diagnostic and therapeutic management of paediatric high grade glioma
Christof Kramm
09:55 – 10:15 Treatment for H3K27M mutation harboring diffuse midline gliomas
Veronica Biassoni
10:15 - 10:35 Customized or randomized approach for H3K27M mutated diffuse midline gliomas?
Jaroslav Štěrba
10:35 – 10:55 Dendritic cell-based immunotherapy in children with high-risk solid tumors: the issues on manufacturing and immune monitoring with focus on pediatric CNS tumors.
Lenka Zdražilová Dubská
10:55 - 11:20 COFFEE BREAK
11:20 – 12:00 Hypofractionation for non-pontine diffuse midline gliomas, Re-irradiation for ped-HGG, Re-re-irradiation for DIPG
Geert Janssens
12:00 – 12:15 Update on the HIT-HGG-2013 trial
Christof Kramm
12:15 – 12:30 Update on the relapsed glioma immunotherapy trial (HIT-HGG Rez Immunovac)
Matthias Eyrich
12:30 – 13:30 LUNCH
13:30 – 14:00 Convection-enhanced Delivery trial in DIPG
David Walker (or representative)
14:00 – 14:30 Infant High-Grade Glioma Registry
Andre Von Bueren
14:30 – 15:00 DIPG Registry Update
Sophie Veldhuijzen - van Zanten
15:00 – 15:30 Precoronary approach for brainstem needle biopsy
Andrea Carai
15:30-16:00 TEA BREAK
16:00 – 16:30 International collaborations with PNOC clinical trial consortium and the DIPG research program in Zürich.
Sabine Mueller
16:30 – 17:00 PRIMAGE: Predictive in-silico multiscale analytics to support personalized cancer diagnosis and prognosis, empowered by imaging biomarkers
Adela Cañete
17:00 – 17:30 Update on multimodal immunotherapy activities in IOZK.
Stefaan van Gool
17:30 – 19:00 Open Brainstorm session:
Future SIOPE trial development in pHGG and DIPG
Development of SIOPE guidelines: Steroids, Palliat
International consultation
Collaborative research projects (+ funding possibilities): Preclinical studies, Clinical Trial, Clinical supportive care studies
SIOPE DIPG Registry discussion: Extension to genomics platforms, Quality of life measurements, Extension to other midline tumors
Any other affairs
19:30 - 21:30 DINNER

January 29, 2019

08:30 – 09:15 DIPG/pHGG derived-exosomes: potentially important for disease monitoring and novel therapeutic strategies
Mass cytometry offers new lenses to look at DIPG and pHGG’s inter- and intratumoral heterogeneity

Mara Vinci
09:15 – 09:45 Establishing preclinical models for novel therapy identification in pediatric brain tumors
Alexander Beck
09:45 – 10:15 Liquid biopsies
Javad Nazarian
10:15 – 10:45 COFFEE BREAK
10:45 – 11:15 Update on the retrospective Gliomatosis Cerebri Project
Gunther Nussbaumer and Christof Kramm
11:45 – 12:00 Closing remarks and conclusions
11:15 – 11:45 Innovation in drug delivery in high-grade glioma and DIPG: convection-enhanced delivery, focused-ultrasound-mediated blood-brain barrier disruption and nanotechnology
Dannis van Vuurden
12:00-13:30 LUNCH
13:45 – 16:00 Mendel Museum of Masaryk University


Hotel Holiday Inn https://www.hibrno.cz/en/ offers a discount to meeting participants. To book your room send an email request to reservations@hibrno.cz including reservation details (room type, arrival, departure) and the promotion code "WINTER SIOPE BRNO".

Meeting rates are 2200 CZK per night for a single room and 2850 CZK per night for a double room.



Daniela Kodytkova

University Hospital Brno, Children´s Hospital
Pediatric Oncology Department

e-mail: kodytkova.daniela@fnbrno.cz